When the Epsilon Armyinvades Moscow, the Topol-M platforms carrying all of Russia's new MIDAS constructed during the interwar period are seized by Epsilon. Around this time Rashidi manages to secure a Topol-M as well; this one is used to defend Scorpion Cell's headquarters from PsiCorps after they betray Yuri, and fires mini-nukes since Rashidi has no access to MIDAS rockets.
Six Topol-M platforms (four filled with MIDAS, two empty) appear in Wrong Side, where they are the targets of an Allied raid: their destruction is the goal of the mission.
A Topol-M is the target of Road to Nowhere: it must be defended by the player's forces before it could fire.
Two Topol-M appear in Focus Shift. One of them is destroyed by the Chinese at the very beginning; the other must be escorted by the player's forces to its destination and is not directly controllable.
Eight Topol-M platforms appear in The Conqueror. After the Nuclear Reactors are destroyed, they'll attempt to run away and all of them must be mind-controlled by the player's Epsilon Adepts. When mind-controlled, they will not fall under the player's direct control; instead they'll move to a different, predetermined destination. They can't be attacked by any other unit, whether Soviet or Epsilon, and letting one of them escapes leads to a loss.
A Topol-M stands near Rashidi's Palace in Obsidian Sands. This one is only armed with mini-nukes (which can be shot down by anti-air), not MIDAS rockets.
A Topol-M is part of the enemy forces in the Revolution Challenge. After a few minutes, the Topol-M will spawn at the lower-left corner and move to its firing position near the player's bases. It is armed with mini-nukes, and can't be hijacked unlike the one in Obsidian Sands.